Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947690 | 1.00 | HRH3 (0.40) | HRH3ALDH1A1L3MBTL1KDM4ETSHR | |
| SCHEMBL6944709 | 1.00 | HRH3 (0.40) | HRH3ALDH1A1L3MBTL1KDM4ETSHR | |
| SCHEMBL8109154 | 1.00 | HRH3 (0.40) | HRH3ALDH1A1L3MBTL1KDM4ETSHR | |
| SCHEMBL8113533 | 0.98 | HRH3 (0.41) | HRH3ALDH1A1L3MBTL1KDM4ETSHR | |
| SCHEMBL6947658 | 0.98 | HRH3 (0.41) | HRH3ALDH1A1L3MBTL1KDM4ETSHR | |
| SCHEMBL6941588 | 0.93 | HRH3 (0.46) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL8114517 | 0.93 | HRH3 (0.46) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL6946156 | 0.88 | LTA4H (0.43) | HRH3ALDH1A1KDM4E | |
| SCHEMBL8108225 | 0.88 | HRH3 (0.40) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL6944340 | 0.88 | HRH3 (0.40) | HRH3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |