Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.39 |
| ▸ | F9 | P00740 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 6/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122589 | 0.95 | ITGB3 (0.42) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL8125479 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL8118290 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL8115483 | 0.85 | ITGB3 (0.32) | ITGB3ITGA2B | |
| SCHEMBL8122698 | 0.85 | F10 (0.41) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL8107033 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL8121578 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL7423343 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL7424212 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BF9F10F2 | |
| SCHEMBL8116922 | 0.82 | F9 (0.39) | ITGB3ITGA2BF9F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |