SCHEMBL8116035

SCHEMBL8116035

CN[C@@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCC(=O)NCCCC[C@H](N)C(=O)NCCCC[C@H](NC)C(N)=O)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.50
▸ DPP7 Q9UHL4 2/20 0.40
▸ GNAI3 P08754 1/20 0.39
▸ GNAO1 P09471 1/20 0.39
▸ GNAI1 P63096 1/20 0.39
▸ NOD1 Q9Y239 2/20 0.39
▸ ALB P02768 1/20 0.37
▸ EPOR P19235 1/20 0.36
▸ RRM1 P23921 1/20 0.35
▸ CD40 P25942 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12972447 0.94 GLP1R (0.50) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL8115663 0.92 GLP1R (0.51) GLP1RALBEPORTSHRMEN1
SCHEMBL15427406 0.92 GLP1R (0.51) GLP1RGNAI3GNAO1GNAI1NOD1
SCHEMBL12743650 0.89 GLP1R (0.48) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL8122831 0.89 GLP1R (0.48) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL12972437 0.87 GLP1R (0.47) GLP1RALBEPORTSHR
SCHEMBL12972442 0.87 GLP1R (0.47) GLP1RALBEPORTSHR
SCHEMBL12147636 0.87 GLP1R (0.47) GLP1RDPP7GNAI3GNAO1GNAI1
SCHEMBL8116615 0.86 GLP1R (0.58) GLP1R
SCHEMBL12972441 0.86 GLP1R (0.68) GLP1RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9056138-B2 Multivalent constructs for therapeutic and diagnostic applications BRACCO SUISSE SA (CH) 2015-06-16 — — US disclosed
US-20140205545-A1 MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS DYAX CORP. (US) 2014-07-24 — — US disclosed
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders ARBOGAST CHRISTOPHE (FR) 2004-10-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140205545-A1 MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS CD47, BCR, CD44 GLP1R 2595/4885DPP7 1750/4885GNAI3 975/4885
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders MKI67, TP53, VHL GLP1R 4619/4885DPP7 3202/4885GNAI3 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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