Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716975 | 0.84 | DAO (0.53) | DAO | |
| SCHEMBL482202 | 0.84 | DAO (0.53) | DAO | |
| SCHEMBL1100359 | 0.76 | DAO (0.61) | DAOCTNNB1TCF7L2ALDH1A1LMNA | |
| SCHEMBL22227188 | 0.76 | DAO (0.61) | DAOCTNNB1TCF7L2 | |
| SCHEMBL3526289 | 0.76 | DAO (0.61) | DAOCTNNB1TCF7L2 | |
| SCHEMBL481926 | 0.76 | DAO (1.00) | DAOCTNNB1TCF7L2ALDH1A1 | |
| SCHEMBL11130742 | 0.76 | DAO (0.61) | DAOALDH1A1LMNAMAPTMAOB | |
| SCHEMBL9411282 | 0.76 | DAO (0.61) | DAOCTNNB1TCF7L2ALDH1A1MAPT | |
| SCHEMBL30182741 | 0.76 | DAO (0.61) | DAOCTNNB1TCF7L2 | |
| SCHEMBL6590835 | 0.73 | MAOB (0.45) | DAOALDH1A1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304205-A | Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-12-29 | — | — | CN | disclosed |
| EP-0971926-A1 | DIHYDROPYRAZINO 1,2-$i(A)-]INDOLE-1-ONE DERIVATIVES, PREPARATION AND APPLICATION THEREOF IN THERAPEUTICS | SANOFI-SYNTHELABO (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042710-A1 | DIHYDROPYRAZINO [1,2-A-]INDOLE-1-ONE DERIVATIVES, PREPARATION AND APPLICATION THEREOF IN THERAPEUTICS | SANOFI-SYNTHELABO (FR) | 1998-10-01 | — | — | WO | disclosed |