SCHEMBL481926

SCHEMBL481926

O=c1[nH]oc2cc(Cl)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DAO P14920 4/20 1.00
▸ CTNNB1 P35222 1/20 0.43
▸ TCF7L2 Q9NQB0 1/20 0.43
▸ PARP1 P09874 1/20 0.43
▸ AHR P35869 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ TTR P02766 1/20 0.40
▸ GRIN2D O15399 1/20 0.39
▸ GRIN3B O60391 1/20 0.39
▸ GRIN1 Q05586 1/20 0.39
▸ GRIN2A Q12879 1/20 0.39
▸ GRIN2B Q13224 1/20 0.39
▸ GRIN2C Q14957 1/20 0.39
▸ GRIN3A Q8TCU5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481873 0.84 DAO (0.72) DAOPARP1AHR
SCHEMBL1100359 0.76 DAO (0.61) DAOCTNNB1TCF7L2PARP1ALDH1A1
SCHEMBL9411282 0.76 DAO (0.61) DAOCTNNB1TCF7L2PARP1ALDH1A1
SCHEMBL3526289 0.76 DAO (0.61) DAOCTNNB1TCF7L2
SCHEMBL482156 0.76 DAO (0.61) DAOAHRALDH1A1TTRGRIN2D
SCHEMBL8116280 0.76 DAO (0.61) DAOCTNNB1TCF7L2ALDH1A1
SCHEMBL30182741 0.76 DAO (0.61) DAOCTNNB1TCF7L2PARP1
SCHEMBL11130742 0.76 DAO (0.61) DAOALDH1A1
SCHEMBL22227188 0.76 DAO (0.61) DAOCTNNB1TCF7L2PARP1
SCHEMBL1071182 0.73 DAO (0.58) DAOPARP1AHRTTRGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119940783-A Design method for enhancing flexibility of low-carbon building energy and interactive friendliness of power grid 中建壹品投资发展有限公司 2025-05-06 — — CN claimed
CN-119809026-A Multi-path optimization method and device for carbon emission reduction in electricity utilization area 国网河北省电力有限公司综合服务中心 2025-04-11 — — CN claimed
CN-119378824-A Life-cycle-based carbon emission accounting method for household garbage fine utilization system 华中科技大学 2025-01-28 — — CN claimed
CN-119180438-A Data-driven optical-biogas virtual power plant two-stage low-carbon scheduling method and system 国网江苏省电力有限公司连云港供电分公司 2024-12-24 — — CN claimed
US-20240368659-A1 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2024-11-07 — — US claimed
CN-118551599-A Multi-field coupling operator splitting solving method and equipment for biological plugging well flow model 广州地铁设计研究院股份有限公司 2024-08-27 — — CN claimed
CN-118095535-A Multi-energy coupling system based on cofiring technology and optimal configuration method thereof 南昌大学 2024-05-28 — — CN claimed
EP-4370653-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS Biosyntia ApS (DK) 2024-05-22 — — EP claimed
CN-117937541-A Rural comprehensive energy system under light and biogas cooperation and optimal operation method 中国矿业大学 2024-04-26 — — CN claimed
US-20240016772-A1 Compositions And Methods Comprising D-Cysteine Or A D-Derivative Thereof UNIVERSITE DE GENEVE (CH) 2024-01-18 — — US claimed
US-11872492-B2 Color blindness diagnostic system ELECTRONIC ARTS INC. (US) 2024-01-16 — — US claimed
EP-4203938-A1 COMPOSITIONS AND METHODS COMPRISING D-CYSTEINE OR A D-DERIVATIVE THEREOF Université de Genève (CH) 2023-07-05 — — EP claimed
US-20230146141-A1 COLOR BLINDNESS DIAGNOSTIC SYSTEM ELECTRONIC ARTS INC. 2023-05-11 — — US claimed
WO-2023285585-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2023-01-19 — — WO claimed
US-20220127311-A1 CELL FACTORIES FOR IMPROVED PRODUCTION OF COMPOUNDS AND PROTEINS DEPENDENT ON IRON SULFUR CLUSTERS BIOSYNTIA APS (DK) 2022-04-28 — — US claimed
WO-2022043265-A1 COMPOSITIONS AND METHODS COMPRISING D-CYSTEINE OR A D-DERIVATIVE THEREOF UNIVERSITÉ DE GENÈVE (CH) 2022-03-03 — — WO claimed
EP-3960168-A1 COMPOSITIONS AND METHODS COMPRISING D-CYSTEINE OR A DERIVATIVE THEREOF Université de Genève (CH) 2022-03-02 — — EP claimed
CN-110389938-B Method for improving safety of relay protection equipment 北京四方继保自动化股份有限公司 2022-02-22 — — CN claimed
US-12636287-B2 Organic compounds INTRA-CELLULAR THERAPIES, INC. (US) 2026-05-26 — — US disclosed
US-20070049556-A1 NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS JANSSEN PHARMACEUTICA N.V. (BE) 2007-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049556-A1 NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS KCNJ2, KCNN1, KCNN3 DAO 4140/4885CTNNB1 1778/4885TCF7L2 2659/4885
US-12636287-B2 Organic compounds PDE1A, PDE1B, PDE5A DAO 834/4885CTNNB1 444/4885TCF7L2 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback