Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121436 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8116373 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8122497 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8114827 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8122224 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8121439 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8116859 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8114779 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8107026 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 | |
| SCHEMBL8107500 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |