Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597137 | 1.00 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL24507808 | 0.83 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL24507809 | 0.83 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL23759216 | 0.82 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL23759215 | 0.82 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL24507968 | 0.82 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL27512854 | 0.81 | CYP3A4 (0.42) | SLC6A3SLC6A2SLC6A4TSHRALDH1A1 | |
| SCHEMBL20440744 | 0.79 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL6599747 | 0.79 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4DHFRTSHR | |
| SCHEMBL20439204 | 0.79 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4DHFRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981526-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-01 | — | — | EP | disclosed |
| WO-1997041119-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |