SCHEMBL8117296

SCHEMBL8117296

COc1ccc([C@@H](CCCN(C)S(=O)(=O)C2CC=CS2)N2Cc3c(cccc3N3CCN(C(C)C)CC3)C2=O)cc1OC

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8115652 0.92 UTS2R (0.75) UTS2R
SCHEMBL8115651 0.92 UTS2R (0.73) UTS2R
SCHEMBL8111153 0.89 UTS2R (0.60) UTS2R
SCHEMBL2350157 0.85 UTS2R (1.00) UTS2R
SCHEMBL14949862 0.81 UTS2R (0.69) UTS2R
SCHEMBL2585279 0.81 UTS2R (0.69) UTS2R
SCHEMBL12456273 0.80 UTS2R (0.73) UTS2R
SCHEMBL12157541 0.80 UTS2R (0.90) UTS2R
SCHEMBL2579249 0.79 UTS2R (0.74) UTS2R
SCHEMBL2579247 0.79 UTS2R (0.68) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008153902-A2 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 2008-12-18 WO disclosed