Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 5/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18731561 | 0.86 | KDM4E (0.43) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| SCHEMBL224770 | 0.76 | KDM4E (1.00) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| Bromide SCHEMBL31020961 | 0.74 | KDM4E (0.96) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| SCHEMBL1501808 | 0.74 | KDM4E (0.61) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| SCHEMBL9324003 | 0.74 | KDM4E (0.61) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| SCHEMBL11000595 | 0.74 | CYP3A4 (0.61) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| SCHEMBL18731544 | 0.72 | IDO1 (0.51) | CYP3A4MAPTIDO1POLB | |
| Bromide SCHEMBL10355410 | 0.72 | CYP3A4 (0.58) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| SCHEMBL8117885 | 0.70 | KDM4E (0.61) | KDM4ECYP3A4MAPTIDO1DYRK1A | |
| SCHEMBL7442855 | 0.69 | KDM4E (0.60) | KDM4ECYP3A4MAPTIDO1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4584259-A1 | CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS | Innovo Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |
| US-20240158370-A1 | CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. | 2024-05-16 | — | — | US | disclosed |
| WO-2024054832-A1 | CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| CN-1109021-C | Method of producing N, N'-diazole compounds | PPG INDUSTRIES INC (US) | 2003-05-21 | — | — | CN | disclosed |
| EP-1019381-A1 | METHOD OF PRODUCING N,N'-DIAZOLE COMPOUNDS | PPG INDUSTRIES, INC. (US) | 2000-07-19 | — | — | EP | disclosed |
| CN-1248247-A | Preparation method of N, N' -diazole compound | PPG INDUSTRIES INC (US) | 2000-03-22 | — | — | CN | disclosed |
| WO-1998031672-A1 | METHOD OF PRODUCING N,N'-DIAZOLE COMPOUNDS | PPG INDUSTRIES OHIO, INC. (US) | 1998-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158370-A1 | CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS | CKS1B, CKS2, MARK1 | KDM4E 1794/4885CYP3A4 3790/4885MAPT 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.