Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.44 |
| ▸ | F9 | P00740 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125479 | 0.94 | ITGB3 (0.41) | ITGB3ITGA2BF9F2F10 | |
| SCHEMBL8118290 | 0.94 | ITGB3 (0.41) | ITGB3ITGA2BF9F2F10 | |
| SCHEMBL8122256 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BF9F2F10 | |
| SCHEMBL9029205 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BF9F2F10 | |
| SCHEMBL8122589 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BF9F2F10 | |
| SCHEMBL9028484 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BF9F2F10 | |
| SCHEMBL8108531 | 0.84 | ITGB3 (0.58) | ITGB3ITGA2BF9 | |
| SCHEMBL7416061 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL8117806 | 0.83 | HTT (0.31) | ITGB3ITGA2B | |
| SCHEMBL8122698 | 0.83 | F10 (0.41) | ITGB3ITGA2BF9F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |