SCHEMBL811787

SCHEMBL811787

[O]C1CCCCCCCCCCCCCCCCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 1/20 0.35
EPHX1 P07099 5/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ADH1A P07327 2/20 0.33
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH4 P08319 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290419 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL812318 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL102554 1.00
SCHEMBL303428 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL650716 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL653884 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL811882 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL4349287 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL4644678 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1
SCHEMBL4643580 1.00 CES2 (0.39) CES2CES1ALDH1A1HSD17B10EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2404949-A1 COPOLYCARBONATE AND OPTICAL LENS Teijin Chemicals, Ltd. (JP) 2012-01-11 EP disclosed
US-20110298143-A1 COPOLYCARBONATE AND OPTICAL LENS TEIJIN CHEMICALS LTD. (JP) 2011-12-08 US disclosed
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed