SCHEMBL81185

SCHEMBL81185

Nc1ccccc1Oc1ccccc1N

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.65
MAPT P10636 1/20 0.65
CRHBP P24387 1/20 0.65
CRHR2 Q13324 1/20 0.65
ALDH1A1 P00352 5/20 0.62
ADRA2B P18089 1/20 0.62
PTGS1 P23219 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
GAA P10253 2/20 0.58
RCE1 Q9Y256 1/20 0.58
ALOX15 P16050 2/20 0.53
CYP3A4 P08684 2/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
IKBKB O14920 1/20 0.48
BRAF P15056 1/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29508342 1.00 KDM4E (0.65) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL30979203 1.00 KDM4E (0.65) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL6293884 0.97 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL6289306 0.97 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL1271684 0.97 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL6293125 0.97 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
Hydrochloric Acid SCHEMBL11737056 0.97 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL1361220 0.97 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL560353 0.97 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
Ammonia Solution, Strong SCHEMBL9643837 0.94 KDM4E (0.60) KDM4EMAPTCRHBPCRHR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120037797-A Azos polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2025-05-27 CN claimed
CN-119912353-A Preparation method of N- (2-ethoxyphenyl) -N' - (2-ethylphenyl) -oxamide 常州永和精细化学有限公司 2025-05-02 CN claimed
CN-119751287-A Synthesis method of N- (2-ethoxyphenyl) -N' - (2-ethylphenyl) -oxamide 常州永和精细化学有限公司 2025-04-04 CN claimed
CN-119661445-A Preparation method of ellastine 新乡学院 2025-03-21 CN claimed
CN-119350254-A Preparation method of iron death inducer Erastin 浙江工业大学 2025-01-24 CN claimed
CN-118221542-A Synthesis method of N- (2-ethoxyphenyl) -N' - (2-ethylphenyl) -oxamide 常州永和精细化学有限公司 2024-06-21 CN claimed
CN-117865820-A Synthesis method of 2,2' -diaminodiphenyl ether 江苏康恒化工有限公司 2024-04-12 CN claimed
CN-117003662-B Novel process for preparing chromatic phenol 唐山华熠实业股份有限公司 2024-02-23 CN claimed
CN-116426130-B Carbon nanohorn modified polyimide resin and application thereof 北京清大际光科技发展有限公司 2024-01-23 CN claimed
EP-0043848-A4 Preparation of moulded objects from injection mouldable amide-imide copolymers. STANDARD OIL CO (US) 1982-05-28 EP claimed
EP-0043848-A1 Preparation of moulded objects from injection mouldable amide-imide copolymers. STANDARD OIL CO (US) 1982-01-20 EP claimed
US-4309528-A FROM FULLY OR PARTICALLY ACYLATED AROMATIC DIAMINES AND TRIMELLITIC ANHYDRIDE STANDARD OIL COMPANY (INDIANA) (US) 1982-01-05 US claimed
WO-1981002014-A1 INJECTION MOLDABLE AMIDE-IMIDE COPOLYMERS STANDARD OIL CO (US) 1981-07-23 WO claimed
US-4231963-A ETHERIFICATION OF ALKALI METAL AMINOPHENOLATE IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1980-11-04 US claimed
US-4224214-A Injection molding of amic acid and amide-imide polymers and molding compositions STANDARD OIL COMPANY (INDIANA) (US) 1980-09-23 US claimed
US-4167620-A Method for heat treating shaped articles of amide-imide or amic acid polymers STANDARD OIL COMPANY (INDIANA) (US) 1979-09-11 US claimed
US-4125717-A NITROSATION OF AMINOPHENOL ETHERS BAYER AKTIENGESELLSCHAFT (DE) 1978-11-14 US claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-4045407-A Process for preparing amideimide polymers in the presence of alcoholic solvent STANDARD OIL COMPANY (INDIANA) (US) 1977-08-30 US claimed