SCHEMBL1361220

SCHEMBL1361220

Nc1ccccc1Oc1ccccc1Oc1ccccc1Oc1ccccc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.62
MAPT P10636 1/20 0.62
CRHBP P24387 1/20 0.62
CRHR2 Q13324 1/20 0.62
ALDH1A1 P00352 5/20 0.59
ADRA2B P18089 1/20 0.59
PTGS1 P23219 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
GAA P10253 2/20 0.56
RCE1 Q9Y256 1/20 0.56
CYP3A4 P08684 2/20 0.50
ALOX15 P16050 2/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
IKBKB O14920 1/20 0.47
BRAF P15056 1/20 0.47
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293884 1.00 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL1271684 1.00 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL6293125 1.00 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL560353 1.00 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL6289306 1.00 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1
Ammonia Solution, Strong SCHEMBL9643837 0.97 KDM4E (0.60) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL81185 0.97 KDM4E (0.65) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL30979203 0.97 KDM4E (0.65) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL29508342 0.97 KDM4E (0.65) KDM4EMAPTCRHBPCRHR2ALDH1A1
Hydrochloric Acid SCHEMBL11737056 0.94 KDM4E (0.62) KDM4EMAPTCRHBPCRHR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997462-A Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1991-03-05 US claimed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP claimed
US-11885694-B2 Temperature sensor element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-30 US disclosed
US-11674920-B2 Moisture-sensitive film and sensor using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-13 US disclosed
CN-112939915-B Diamine monomer for photosensitive resin, polyimide precursor, photosensitive resin composition, and use thereof 武汉柔显科技股份有限公司 2022-10-14 CN disclosed
CN-108690193-B Polyimide, adhesive material, adhesive layer, adhesive sheet, copper foil, copper-clad laminate, wiring board, and method for producing same 荒川化学工业株式会社 2022-09-09 CN disclosed
CN-108690552-B Adhesive, adhesive material, adhesive layer, adhesive sheet, copper foil, copper-clad laminate, wiring board, and method for producing same 荒川化学工业株式会社 2022-04-19 CN disclosed
US-20220082452-A1 TEMPERATURE SENSOR ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-03-17 US disclosed
CN-107793991-B Copper-clad laminate for flexible printed wiring board, and flexible printed wiring board 荒川化学工业株式会社 2022-03-08 CN disclosed
US-20220065708-A1 TEMPERATURE SENSOR ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-03-03 US disclosed
US-20220065707-A1 TEMPERATURE SENSOR ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-03-03 US disclosed
EP-1388758-A1 Photosensitive heat resistant resin precursor composition TORAY INDUSTRIES, INC. (JP) 2004-02-11 EP disclosed
US-20030092870-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1296540-A1 DISPLAY TORAY INDUSTRIES, INC. (JP) 2003-03-26 EP disclosed
EP-1288191-A2 Novel aromatic diamine and polyimide thereof Mitsui Chemicals, Inc. (JP) 2003-03-05 EP disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed
US-6090525-A PHOTOSENSITIVE POLYIMIDE COATING AGENT COMPOSITION WITH BOTH GOOD VISCOSITY STABILITY AT ROOM TEMPERATURE WITH LAPSE OF TIME AND GOOD PHOTOSENSITIVE PERFORMANCE TORAY INDUSTRIES, INC. (JP) 2000-07-18 US disclosed
EP-0878740-A1 Radiation sensitive polymer composition TORAY INDUSTRIES, INC. (JP) 1998-11-18 EP disclosed
US-4997462-A Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1991-03-05 US disclosed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092870-A1 Novel aromatic diamine and polyimide thereof DDT, AOC1, H1-4 KDM4E 228/4885MAPT 471/4885CRHBP 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.