Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889925 | 0.77 | CHRNA7 (0.37) | CHRNA7 | |
| SCHEMBL25588446 | 0.76 | CHRNA7 (0.36) | CHRNA7 | |
| SCHEMBL8126732 | 0.76 | CTSD (0.35) | — | |
| SCHEMBL2529266 | 0.76 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL20891222 | 0.75 | SYK (0.41) | CHRNA7 | |
| SCHEMBL20890030 | 0.73 | CHRNA7 (0.35) | CHRNA7 | |
| SCHEMBL8402527 | 0.73 | CHRNA7 (0.35) | CHRNA7 | |
| SCHEMBL25694465 | 0.73 | CHRNA7 (0.35) | CHRNA7 | |
| SCHEMBL19343285 | 0.72 | IDH1 (0.37) | CHRNA7 | |
| SCHEMBL10141644 | 0.72 | CHRNA7 (0.34) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306136-A1 | Substituted Ureas and Carbamates | ELAN PHARMACEUTICALS, INC. | 2008-12-11 | — | — | US | disclosed |
| US-7351738-B2 | Substituted ureas and carbamates | ELAN PHARMACEUTICALS, INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-20040209925-A1 | Substituted ureas and carbamates | ELAN PHARMACEUTICALS, INC. | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209925-A1 | Substituted ureas and carbamates | BACE1, BACE2, PSEN1 | CHRNA7 456/4885 |
| US-20080306136-A1 | Substituted Ureas and Carbamates | BACE1, BACE2, APP | CHRNA7 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.