Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.36 |
| ▸ | NPY1R | P25929 | 9/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.36 |
| ▸ | NPY2R | P49146 | 5/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651754 | 0.90 | NPY4R (0.39) | NPY4RNPY1RNPY5RNPY2RPYGL | |
| SCHEMBL8122077 | 0.88 | EPOR (0.39) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8127572 | 0.86 | HDAC3 (0.40) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8125787 | 0.82 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4651752 | 0.79 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RPYGL | |
| SCHEMBL9201861 | 0.78 | TRPV1 (0.41) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4650760 | 0.78 | TRPV1 (0.41) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8127029 | 0.78 | NPY1R (0.41) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8119701 | 0.78 | NPY4R (0.39) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8123562 | 0.77 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |