Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.39 |
| ▸ | NPY1R | P25929 | 10/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.39 |
| ▸ | NPY2R | P49146 | 5/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125787 | 0.87 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RITGB3 | |
| SCHEMBL8127029 | 0.85 | NPY1R (0.41) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8122077 | 0.82 | EPOR (0.39) | NPY4RNPY1RNPY5RNPY2RITGB3 | |
| SCHEMBL8123562 | 0.80 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8127572 | 0.80 | HDAC3 (0.40) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9195765 | 0.79 | TP53 (0.40) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8112714 | 0.79 | MEN1 (0.42) | ITGB3ITGA2B | |
| SCHEMBL8112784 | 0.79 | CNR1 (0.41) | — | |
| SCHEMBL8120666 | 0.78 | NPY4R (0.35) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8119244 | 0.78 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |