Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.53 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119688 | 1.00 | GRIA1 (0.53) | GRIA1GRIA3SLC7A11KDM4EMEN1 | |
| SCHEMBL7049750 | 0.86 | GRIA1 (0.40) | GRIA1GRIA3SLC7A11GRIK1GRIA2 | |
| SCHEMBL7371185 | 0.86 | GRIA1 (0.40) | GRIA1GRIA3SLC7A11GRIK1GRIA2 | |
| SCHEMBL19668565 | 0.81 | KDM4E (0.42) | KDM4EMEN1MAPK1KMT2AMCL1 | |
| SCHEMBL8135086 | 0.81 | MCL1 (0.41) | KDM4EMEN1MAPK1KMT2ACYP2C19 | |
| SCHEMBL7402019 | 0.81 | GRIA1 (0.46) | GRIA1GRIA3KDM4EGRIK1GRIA2 | |
| SCHEMBL7406133 | 0.81 | GRIA1 (0.58) | GRIA1GRIA3KDM4EGRIK1GRIA2 | |
| SCHEMBL7402024 | 0.81 | GRIA1 (0.46) | GRIA1GRIA3KDM4EGRIK1GRIA2 | |
| SCHEMBL7406142 | 0.81 | GRIA1 (0.58) | GRIA1GRIA3KDM4EGRIK1GRIA2 | |
| SCHEMBL27353038 | 0.79 | MCL1 (0.42) | KDM4EMEN1MAPK1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994107-A1 | 5-Arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds | H. LUNDBECK A/S (DK) | 2000-04-19 | — | — | EP | disclosed |
| CN-1136810-A | 5-arylisoxazol-4-yl-substituted 2-aminocarboxylic acid compounds | LUNDBECK & CO AS H (DK) | 1996-11-27 | — | — | CN | disclosed |