Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121354 | 0.87 | PTGER4 (0.54) | MCHR1PTGER4CA1CA2ITGB3 | |
| SCHEMBL8112529 | 0.84 | HDAC1 (0.64) | MCHR1PTGER4HDAC1ITGB3ITGAV | |
| SCHEMBL5651770 | 0.81 | PTGER4 (0.51) | PTGER4F10PLGPRSS1HDAC1 | |
| SCHEMBL8126906 | 0.80 | PTGER4 (0.51) | PTGER4ITGB3ITGAV | |
| SCHEMBL17133717 | 0.79 | CA1 (0.62) | PTGER4CA1CA2ITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL17133671 | 0.78 | CA1 (0.61) | PTGER4CA1CA2ITGB3ITGAV | |
| SCHEMBL10026321 | 0.78 | PDE4A (0.67) | MCHR1PTGER4CA1CA2 | |
| SCHEMBL8112041 | 0.78 | NPY1R (0.64) | — | |
| SCHEMBL8121288 | 0.77 | SIRT5 (0.49) | PTGER4ITGB3ITGAV | |
| SCHEMBL5655200 | 0.76 | HDAC1 (0.58) | MCHR1PTGER4HDAC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |