Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 15/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120885 | 0.86 | NPY1R (0.55) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8119503 | 0.86 | NPY1R (0.53) | NPY1RCNR1NPY5RNPY2RNPY4R | |
| SCHEMBL8526195 | 0.85 | NPY1R (0.52) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8120837 | 0.85 | NPY1R (0.50) | NPY1RNPY5RNPY2RNPY4RNPFFR1 | |
| SCHEMBL8121592 | 0.85 | CNR1 (0.47) | NPY1RCNR1NPY5RNPY2RNPY4R | |
| SCHEMBL7037325 | 0.83 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY2RNPY4R | |
| SCHEMBL8121280 | 0.83 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY2RNPY4R | |
| SCHEMBL7042405 | 0.83 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY2RNPY4R | |
| SCHEMBL7037336 | 0.83 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY2RNPY4R | |
| SCHEMBL7042397 | 0.83 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |