Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.93 |
| ▸ | DRD2 | P14416 | 3/20 | 0.70 |
| ▸ | DRD4 | P21917 | 3/20 | 0.70 |
| ▸ | DRD3 | P35462 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117971 | 0.96 | SIGMAR1 (1.00) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL8119272 | 0.94 | SIGMAR1 (0.82) | SIGMAR1DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8111456 | 0.93 | SIGMAR1 (0.80) | SIGMAR1DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8122294 | 0.91 | SIGMAR1 (0.77) | SIGMAR1DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8120009 | 0.89 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8126235 | 0.89 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8127075 | 0.89 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD3L3MBTL1 | |
| SCHEMBL8124961 | 0.89 | SIGMAR1 (0.74) | SIGMAR1DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8125940 | 0.89 | SIGMAR1 (0.74) | SIGMAR1DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8120491 | 0.89 | SIGMAR1 (0.74) | SIGMAR1DRD2DRD4DRD3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861252-B1 | NAPHTHAMIDE DERIVATIVES OF 3 BETA-AMINO AZABICYCLO OCTANE OR NONANE AS NEUROLEPTIC AGENTS | PF MEDICAMENT (FR) | 2000-02-23 | — | — | EP | claimed |