⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990084 | 0.90 | — | — | |
| SCHEMBL1865543 | 0.78 | ATM (0.42) | — | |
| SCHEMBL4321186 | 0.76 | — | — | |
| SCHEMBL185632 | 0.76 | — | — | |
| SCHEMBL15614617 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL4325316 | 0.75 | RAB9A (0.40) | — | |
| SCHEMBL25278363 | 0.73 | EPHX2 (0.31) | — | |
| SCHEMBL15914451 | 0.73 | EPHX2 (0.31) | — | |
| SCHEMBL14737868 | 0.73 | EPHX2 (0.31) | — | |
| SCHEMBL3409533 | 0.73 | NAMPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665724-A1 | TYPE II TOPOISOMERASE INHIBITORS AND METHODS OF MAKING AND USING THEREOF | Ohio State Innovation Foundation (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173781-A1 | TYPE II TOPOISOMERASE INHIBITORS AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-102186845-B | S1P receptor modulators and their purposes | 阿卡制药有限公司 | 2016-09-07 | — | — | CN | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |