Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680960 | 0.91 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL10236401 | 0.91 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL408875 | 0.88 | SMN1; SMN2 (0.44) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL5505807 | 0.88 | SMN1; SMN2 (0.44) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL19853293 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL19853319 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL601117 | 0.84 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL17841757 | 0.84 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL17922948 | 0.84 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 | |
| SCHEMBL601118 | 0.84 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2BTKCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000030-A1 | PIPERIDINE OLIGOMERS AND COMBINATORIAL LIBRARIES THEREOF | Phytera Symbion ApS (DK) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999003832-A1 | PIPERIDINE OLIGOMERS AND COMBINATORIAL LIBRARIES THEREOF | PHYTERA SYMBION APS (DK) | 1999-01-28 | — | — | WO | disclosed |