Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489570 | 0.71 | DAO (0.33) | — | |
| SCHEMBL18914637 | 0.71 | CHRM1 (0.36) | HRH3 | |
| SCHEMBL24346840 | 0.70 | DAO (0.35) | — | |
| SCHEMBL21876955 | 0.69 | SMPD1 (0.38) | HRH3 | |
| SCHEMBL7311003 | 0.67 | MRGPRX4 (0.38) | — | |
| SCHEMBL19287122 | 0.66 | KDM4E (0.45) | — | |
| SCHEMBL17122452 | 0.66 | SMPD1 (0.43) | HRH3 | |
| SCHEMBL26132404 | 0.66 | DAO (0.32) | — | |
| SCHEMBL13762097 | 0.66 | MEN1 (0.37) | — | |
| SCHEMBL9393479 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691962-B1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| WO-1994022842-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |