Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 15/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120804 | 0.89 | NPY1R (0.58) | NPY1RCA1CA2NPFFR1NPFFR2 | |
| SCHEMBL8112857 | 0.87 | CA2 (0.52) | NPY1RCA1CA2NPFFR1NPFFR2 | |
| SCHEMBL8123411 | 0.86 | NPY1R (0.57) | NPY1RNPFFR1NPFFR2NPY5RGRIA1 | |
| SCHEMBL8124246 | 0.86 | NPY1R (0.72) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8119387 | 0.84 | NPY1R (0.45) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8125986 | 0.84 | NPY1R (0.60) | NPY1RNPFFR1NPFFR2NPY5RGRIA1 | |
| SCHEMBL8125831 | 0.84 | NPY1R (0.53) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8120056 | 0.84 | NPY1R (0.60) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8126146 | 0.84 | NPY1R (0.53) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8127620 | 0.84 | MCHR1 (0.56) | NPY1RNPFFR1NPFFR2NPY5RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |