SCHEMBL812196

SCHEMBL812196

CCCCC(CC)COC(=O)c1ccc(C(=O)O)cc1C

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.71
TSHR P16473 4/20 0.71
MAPK1 P28482 3/20 0.71
CYP3A4 P08684 3/20 0.64
CA2 P00918 1/20 0.64
LMNA P02545 3/20 0.58
PRSS1 P07477 1/20 0.57
PRSS2 P07478 1/20 0.57
PRSS3 P35030 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 1/20 0.46
MAPT P10636 1/20 0.44
RARB P10826 1/20 0.40
RECQL P46063 1/20 0.40
ESR1 P03372 1/20 0.39
PLA2G4B P0C869 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30620420 1.00 ALDH1A1 (0.71) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL812195 0.92 ALDH1A1 (0.83) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL828867 0.91 ALDH1A1 (0.85) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL29659258 0.90 ALDH1A1 (0.79) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL174632 0.90 ALDH1A1 (0.79) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL4141137 0.90 ALDH1A1 (0.79) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL27631103 0.89 ALDH1A1 (0.77) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL2467994 0.87 ALDH1A1 (0.70) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL2131653 0.87 ALDH1A1 (0.67) ALDH1A1TSHRMAPK1CYP3A4CA2
SCHEMBL19288933 0.87 ALDH1A1 (0.67) ALDH1A1TSHRMAPK1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2689643-A1 THERMAL MANAGEMENT WITHIN AN LED ASSEMBLY Dow Corning Corporation (US) 2014-01-29 EP claimed
US-20130344632-A1 Thermal Management Within an LED Assembly DOW CORNING CORPORATION (US) 2013-12-26 US claimed
US-8440312-B2 Thermal interface materials and methods for their preparation and use DOW CORNING CORPORATION (US) 2013-05-14 US claimed
WO-2012128875-A1 THERMAL MANAGEMENT WITHIN AN LED ASSEMBLY DOW CORNING CORPORATION (US) 2012-09-27 WO claimed
EP-2406321-A1 THERMAL INTERFACE MATERIALS AND METHODS FOR THEIR PREPARATION AND USE Dow Corning Corporation (US) 2012-01-18 EP claimed
US-20110311767-A1 Thermal Interface Materials and Methods for Their Preparation and Use DOW CORNING CORPORATION 2011-12-22 US claimed
WO-2010104534-A1 THERMAL INTERFACE MATERIALS AND MEHTODS FOR THEIR PREPARATION AND USE DOW CORNING CORPORATION (US) 2010-09-16 WO claimed
EP-4519346-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-12428561-B2 Silicone-polyether copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2025-09-30 US disclosed
US-20250257169-A1 COMPOSITION, URETHANE PREPOLYMER, AND RELATED METHODS AND USES DOW SILICONES CORP (US) 2025-08-14 US disclosed
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions DOW SILICONES CORPORATION (US) 2025-08-05 US disclosed
US-12344712-B2 Silicone-poly acrylate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2025-07-01 US disclosed
EP-3898782-B1 SILICONE-POLYACRYLATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2025-06-25 EP disclosed
WO-2012134784-A1 COMPOSITIONS CONTAINING PHOSPHONATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134786-A1 COMPOSITIONS CONTINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012128875-A1 THERMAL MANAGEMENT WITHIN AN LED ASSEMBLY DOW CORNING CORPORATION (US) 2012-09-27 WO disclosed
EP-2406321-A1 THERMAL INTERFACE MATERIALS AND METHODS FOR THEIR PREPARATION AND USE Dow Corning Corporation (US) 2012-01-18 EP disclosed
US-20110311767-A1 Thermal Interface Materials and Methods for Their Preparation and Use DOW CORNING CORPORATION 2011-12-22 US disclosed
WO-2011072056-A2 CURE RATE CONTROL FOR ALKOXYSILYL-END-BLOCKED POLYMERS DOW CORNING COPORATION (US) 2011-06-16 WO disclosed
WO-2010104534-A1 THERMAL INTERFACE MATERIALS AND MEHTODS FOR THEIR PREPARATION AND USE DOW CORNING CORPORATION (US) 2010-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions MSR1, OXSR1, RIOX2 ALDH1A1 1749/4885TSHR 2322/4885MAPK1 4154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.