Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123283 | 0.84 | TLR7 (0.60) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL3518335 | 0.82 | TLR7 (0.65) | TLR7NUDT1LMNAPOLBHRH2 | |
| Bromide SCHEMBL5805007 | 0.81 | TLR7 (0.64) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL6105045 | 0.78 | TLR7 (0.60) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL27365707 | 0.75 | TLR7 (0.69) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL11249941 | 0.75 | MEN1 (0.57) | HTR2AADRA1AMEN1KMT2ATSHR | |
| SCHEMBL22043512 | 0.75 | TLR7 (0.62) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL30773474 | 0.75 | TLR7 (0.73) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22803659 | 0.75 | TLR7 (0.73) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22803781 | 0.75 | TLR7 (0.65) | TLR7NUDT1LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603251-B1 | 1-SUBSTITUTED 1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES; INTERMEDIATE AND PHARMACEUTICAL COMPOSITIONS | MINNESOTA MINING & MFG (US) | 2000-10-18 | — | — | EP | disclosed |
| US-5525612-A | ANTIVIRAL PHARMACEUTICAL COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-06-11 | — | — | US | disclosed |
| US-5346905-A | Induce interferon biosynthesis; viricides, effective against herpes virus; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0603251-A1 | 1-SUBSTITUTED 1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES; INTERMEDIATE AND PHARMACEUTICAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5268376-A | Containing alkoxy substitution | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1993005042-A1 | 1-SUBSTITUTED 1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES; INTERMEDIATE AND PHARMACEUTICAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-03-18 | — | — | WO | disclosed |