Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821130 | 0.79 | KMT2A (0.42) | KMT2AMAPK1MAOAMAOBKDM1A | |
| SCHEMBL8113519 | 0.78 | CYP2A6 (0.35) | KMT2AMAPK1MAOAMAOBMEN1 | |
| SCHEMBL8117721 | 0.78 | MAOB (0.36) | KMT2AMAOAMAOBMEN1HSD11B1 | |
| SCHEMBL8116256 | 0.77 | MEN1 (0.56) | KMT2AMAPK1MEN1LMNACYP2C9 | |
| SCHEMBL8121636 | 0.76 | SLC6A4 (0.40) | KMT2AMEN1HSD11B1BACE1SLC6A4 | |
| SCHEMBL9735920 | 0.71 | CCNB2 (0.47) | MAOAMAOBKDM1ALMNACYP2A6 | |
| SCHEMBL12920578 | 0.68 | MAOB (0.39) | KMT2AMAOAMAOBMEN1HSD11B1 | |
| SCHEMBL15763621 | 0.67 | MEN1 (0.60) | KMT2AMAPK1MEN1LMNACYP2C9 | |
| SCHEMBL8118617 | 0.67 | TP53 (0.43) | LMNAHDAC4AHRSLC6A4 | |
| SCHEMBL3279419 | 0.65 | MAPK1 (0.44) | KMT2AMAPK1MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |