Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764806 | 0.83 | DRD2 (0.64) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL9694527 | 0.82 | MAOB (0.47) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL9694893 | 0.82 | MAOA (0.52) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL17157074 | 0.81 | NR1I2 (0.42) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL19433337 | 0.79 | TP53 (0.43) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL31210280 | 0.79 | OPRM1 (0.59) | LMNASLC6A4SLC6A3HSD11B1ALDH1A1 | |
| SCHEMBL31210281 | 0.79 | OPRM1 (0.59) | LMNASLC6A4SLC6A3HSD11B1ALDH1A1 | |
| SCHEMBL11990211 | 0.78 | ESR1 (0.50) | SLC6A4SLC6A3ESR1ESR2HSD11B1 | |
| SCHEMBL14260455 | 0.78 | ESR1 (0.80) | SLC6A4SLC6A3ESR1ESR2HSD11B1 | |
| Iodide SCHEMBL31210277 | 0.78 | CCNB2 (0.40) | CCNB2CDK1CCNB1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134152-A | 1,2,4-Triazole compounds | SANKYO COMPANY, LIMITED (JP) | 1992-07-28 | — | — | US | disclosed |