Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121398 | 0.90 | KCNH2 (0.76) | ABCB1 | |
| SCHEMBL8115469 | 0.87 | ABCB1 (0.70) | ABCB1 | |
| SCHEMBL8910031 | 0.87 | ABCB1 (0.63) | ABCB1 | |
| SCHEMBL8117499 | 0.87 | ABCB1 (0.65) | ABCB1 | |
| SCHEMBL29374303 | 0.86 | ABCB1 (1.00) | ABCB1 | |
| SCHEMBL8110927 | 0.84 | ABCB1 (0.71) | ABCB1 | |
| SCHEMBL8911001 | 0.83 | ABCB1 (0.60) | ABCB1 | |
| SCHEMBL31429551 | 0.82 | ABCB1 (0.90) | ABCB1 | |
| SCHEMBL8118006 | 0.81 | ABCB1 (0.56) | ABCB1 | |
| SCHEMBL9037392 | 0.78 | ALDH1A1 (0.58) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691962-B1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |