Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 18/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 18/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 18/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 18/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 18/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 18/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8126031 | 0.91 | PSEN1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8112073 | 0.84 | PSEN1 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9196942 | 0.82 | NPY4R (0.33) | — | |
| SCHEMBL1388296 | 0.76 | TACR1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8111831 | 0.75 | TRPM8 (0.36) | — | |
| SCHEMBL1388418 | 0.75 | TMEM97 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4650701 | 0.75 | CNR1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL8126105 | 0.74 | TMEM97 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7751927 | 0.72 | F7 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Hydrochloric Acid SCHEMBL8123651 | 0.72 | CNR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |