Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.86 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.76 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | GAPDH | P04406 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107293 | 0.93 | ADORA3 (1.00) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL28585336 | 0.91 | ADORA3 (0.74) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL8116456 | 0.88 | ADORA3 (0.82) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL8115217 | 0.87 | ADORA3 (0.80) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL8115882 | 0.87 | ADORA3 (0.80) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL8122887 | 0.87 | ADORA3 (0.80) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL8116819 | 0.86 | ADORA3 (0.80) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL28585964 | 0.83 | ADORA3 (0.72) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL8116146 | 0.83 | ADORA3 (0.73) | ADORA3ADORA2AADORA1TMIGD3NPC1 | |
| SCHEMBL8117382 | 0.80 | ADORA2A (0.78) | ADORA3ADORA2AADORA1TMIGD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020130120-A1 | CANCER METASTASIS INHIBITOR | 学校法人京都薬科大学 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020130120-A1 | CANCER METASTASIS INHIBITOR | 学校法人京都薬科大学 | 2020-06-25 | — | — | WO | disclosed |
| EP-0645382-B1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5574062-A | COMPOUNDS HAVE 3-ARYL AND 7-HYDROXY OR -ACYLOXY; USE TO INHIBIT 12-LIPOXYGENASE | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0645382-A1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |