Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.62 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271705 | 1.00 | DPP4 (0.62) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL3508104 | 1.00 | DPP4 (0.62) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL29752493 | 1.00 | DPP4 (0.62) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL8271030 | 1.00 | DPP4 (0.62) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL8127608 | 1.00 | DPP4 (0.62) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL15847121 | 1.00 | DPP4 (0.62) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL17598284 | 0.91 | DPP4 (0.62) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL15927521 | 0.90 | DPP4 (0.57) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL8328208 | 0.88 | DPP4 (0.46) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL14532904 | 0.88 | DPP4 (0.46) | DPP4CYP3A4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802715-B2 | Crystal forms of saxagliptin and processes for preparing same | ASTRAZENECA AB (SE) | 2014-08-12 | — | — | US | disclosed |
| WO-2008131149-A2 | CRYSTAL FORMS OF SAXAGLIPTIN AND PROCESSES FOR PREPARING SAME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-10-30 | — | — | WO | disclosed |