Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14532904 | 1.00 | DPP4 (0.46) | DPP4DPP8DPP9CYP3A4FAP | |
| SCHEMBL12968316 | 0.89 | DPP4 (0.48) | DPP4DPP8DPP9CYP3A4FAP | |
| SCHEMBL29752493 | 0.88 | DPP4 (0.62) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL3508104 | 0.88 | DPP4 (0.62) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL8123723 | 0.88 | DPP4 (0.62) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL8271030 | 0.88 | DPP4 (0.62) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL11960035 | 0.88 | DPP4 (0.43) | DPP4DPP8DPP9CYP3A4FAP | |
| SCHEMBL8271705 | 0.88 | DPP4 (0.62) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL15847121 | 0.88 | DPP4 (0.62) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL8127608 | 0.88 | DPP4 (0.62) | DPP4DPP8DPP9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2505578-A2 | Methods and Compounds for Producing Dipeptidyl Peptidase IV Inhibitors and Intermediates thereof | Bristol-Myers Squibb Company (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2004052850-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |