Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121433 | 0.93 | HPGD (0.52) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8124848 | 0.92 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8121621 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8115643 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8106868 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8121136 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8105934 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8105695 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8116042 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8114900 | 0.91 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |