SCHEMBL8124186

SCHEMBL8124186

COCc1cc(CO[PH](=O)OCc2cc(COC)no2)on1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.30
PPARA Q07869 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8123160 0.93 DAO (0.33) MEN1KMT2AALDH1A1PPARANPC1
SCHEMBL8124187 0.87 ALDH1A1 (0.33) MEN1KMT2AALDH1A1PPARANPC1
SCHEMBL8123162 0.81 DAO (0.34) MEN1KMT2AALDH1A1PPARANPC1
SCHEMBL8116548 0.78 CHRM1 (0.41) MEN1KMT2AALDH1A1NPC1POLB
SCHEMBL14069081 0.77 PPARA (0.33) MEN1KMT2APKMPPARANPC1
SCHEMBL4157127 0.75 NOTUM (0.41) MEN1KMT2APKM
SCHEMBL8119822 0.75 MEN1 (0.32) MEN1KMT2APKMPOLB
SCHEMBL7993892 0.75 ALDH1A1 (0.37) MEN1KMT2AALDH1A1PKMNPC1
SCHEMBL12489570 0.75 DAO (0.33) MEN1KMT2APPARANPC1POLB
SCHEMBL8117751 0.73 PPARA (0.41) ALDH1A1PPARAPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691962-B1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AG (DE) 2000-09-13 EP disclosed
EP-0691962-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1996-01-17 EP disclosed
WO-1994022842-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1994-10-13 WO disclosed