Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | FPR2 | P25090 | 8/20 | 0.35 |
| ▸ | FPR1 | P21462 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8124196 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL27439133 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL8117121 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BFPR2FPR1CTSK | |
| Trifluoroacetic Acid SCHEMBL8123151 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BCTSKCTSBCTSS | |
| SCHEMBL8116538 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BCTSKCTSBCTSS | |
| Trifluoroacetic Acid SCHEMBL7411886 | 0.79 | ITGB3 (0.65) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL7417149 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL7424548 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL7422393 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL8109889 | 0.77 | ITGB3 (0.45) | ITGB3ITGA2BCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |