Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | USP2 | O75604 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763793 | 0.83 | ALDH1A1 (0.37) | SYKRXFP1HPGDHTTPOLB | |
| SCHEMBL4763795 | 0.83 | ALDH1A1 (0.37) | SYKRXFP1HPGDHTTPOLB | |
| SCHEMBL4772928 | 0.82 | ALDH1A1 (0.35) | SYKRXFP1MAPTUSP2TSHR | |
| SCHEMBL4770809 | 0.82 | KDM4E (0.38) | SYKRXFP1HPGDHTTPOLB | |
| SCHEMBL4791404 | 0.82 | SYK (0.33) | SYKRXFP1HPGDPOLBMAPT | |
| SCHEMBL4791402 | 0.82 | SYK (0.33) | SYKRXFP1HPGDPOLBMAPT | |
| SCHEMBL4764376 | 0.80 | RXFP1 (0.36) | SYKRXFP1HPGDHTTPOLB | |
| SCHEMBL4764095 | 0.80 | RXFP1 (0.35) | SYKRXFP1HPGDHTTMAPT | |
| SCHEMBL4764086 | 0.80 | RXFP1 (0.35) | SYKRXFP1HPGDHTTMAPT | |
| SCHEMBL14102734 | 0.80 | CHEK1 (0.43) | SYKRXFP1HPGDHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |