Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115633 | 0.99 | TSHR (0.57) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL8109384 | 0.96 | TSHR (0.55) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL8119201 | 0.91 | GRIN2D (0.56) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL27970683 | 0.86 | TSHR (0.66) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL7107686 | 0.85 | TSHR (0.68) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL28355616 | 0.85 | TSHR (0.68) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL10684173 | 0.85 | TSHR (0.68) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL28099429 | 0.85 | TSHR (0.68) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL27509713 | 0.85 | TSHR (0.68) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL28099572 | 0.85 | TSHR (0.68) | TSHRMAPK1TP53CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060602-A | Compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 2000-05-09 | — | — | US | disclosed |
| EP-0747369-B1 | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO KK (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5917046-A | Method for producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 1999-06-29 | — | — | US | disclosed |
| US-5714613-A | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0747369-A1 | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO Inc. (JP) | 1996-12-11 | — | — | EP | disclosed |