Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109384 | 0.92 | TSHR (0.55) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8124252 | 0.91 | TSHR (0.56) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8115633 | 0.89 | TSHR (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL8118387 | 0.88 | MAOA (0.60) | GRIN2DGRIN2AGRIN2BGRIN2CKDM4E | |
| SCHEMBL3896579 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2HSD17B10LMNA | |
| SCHEMBL8117695 | 0.82 | GRIN2D (0.55) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL2239095 | 0.80 | GRIN2D (0.65) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL28445108 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10LMNATDP1 | |
| SCHEMBL11060407 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAOBHSD17B10LMNA | |
| SCHEMBL8123886 | 0.79 | TDP1 (0.61) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060602-A | Compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 2000-05-09 | — | — | US | disclosed |
| EP-0747369-B1 | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO KK (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5917046-A | Method for producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 1999-06-29 | — | — | US | disclosed |
| US-5714613-A | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0747369-A1 | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO Inc. (JP) | 1996-12-11 | — | — | EP | disclosed |