Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.78 |
| ▸ | MEN1 | O00255 | 8/20 | 0.78 |
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | GLA | P06280 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | ATM | Q13315 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | IGLV6-57 | P01721 | 4/20 | 0.58 |
| ▸ | CASP1 | P29466 | 4/20 | 0.58 |
| ▸ | CASP7 | P55210 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115960 | 0.88 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1MAPTGLA | |
| SCHEMBL29593308 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTGLA | |
| SCHEMBL1942067 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTGLA | |
| SCHEMBL8115670 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1MAPTGLA | |
| SCHEMBL8123348 | 0.83 | PIM1 (0.58) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL1771392 | 0.79 | AR (0.59) | ALDH1A1KMT2AMEN1MAPTGLA | |
| SCHEMBL8116718 | 0.77 | ALDH1A1 (0.79) | ALDH1A1KMT2AMEN1MAPTGLA | |
| SCHEMBL5084318 | 0.76 | PIM1 (0.58) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL8122108 | 0.74 | ALDH1A1 (0.75) | ALDH1A1KMT2AMEN1MAPTGLA | |
| SCHEMBL7640717 | 0.74 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |