Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079665 | 0.83 | KDM4E (0.58) | L3MBTL1HTTATMKDM4ERAB9A | |
| SCHEMBL11079422 | 0.81 | L3MBTL1 (0.46) | L3MBTL1HTTATMKDM4ESMN1; SMN2 | |
| SCHEMBL11076535 | 0.81 | L3MBTL1 (0.46) | L3MBTL1HTTATMKDM4ERAB9A | |
| SCHEMBL11079333 | 0.81 | HTT (0.46) | L3MBTL1HTTATMKDM4ESMN1; SMN2 | |
| SCHEMBL1645738 | 0.80 | L3MBTL1 (1.00) | L3MBTL1HTTATMKDM4ERAB9A | |
| SCHEMBL8122403 | 0.78 | HTT (0.45) | L3MBTL1HTTATMKDM4ESMN1; SMN2 | |
| SCHEMBL8123430 | 0.78 | L3MBTL1 (0.54) | L3MBTL1HTTATMKDM4ERAB9A | |
| SCHEMBL4635494 | 0.77 | L3MBTL1 (0.59) | L3MBTL1HTTATMKDM4ERAB9A | |
| SCHEMBL11185924 | 0.76 | L3MBTL1 (0.46) | L3MBTL1HTTATMKDM4ERAB9A | |
| SCHEMBL27922094 | 0.75 | L3MBTL1 (0.72) | L3MBTL1HTTATMKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519353-B1 | Indolizin derivatives, process for their preparation and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5334716-A | Preventing testosteron 5a-reductase mediated diseases; alopecia, acne, prostatism | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0519353-A2 | Indolizin derivatives, process for their preparation and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |