SCHEMBL812441

SCHEMBL812441

CCCCCCCC[SiH2]Cl

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
DNM1 Q05193 7/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28662644 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL15796294 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL3392994 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL10833640 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL17966562 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9438692 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL4358183 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL7649056 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL303415 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL132944 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431151-A Method for desalting and dewatering emulsified nitrobenzene 中国石油化工股份有限公司 2025-02-14 CN claimed
US-20230331765-A1 METHODS AND DEVICES FOR DE NOVO OLIGONUCLEIC ACID ASSEMBLY TWIST BIOSCIENCE CORP (US) 2023-10-19 US claimed
US-11697668-B2 Methods and devices for de novo oligonucleic acid assembly Twist Bioscience Corporation 2023-07-11 US claimed
CN-115138411-A Hydrophilic and hydrophobic grid chip, preparation method and application thereof 深圳市曙芯生物科技有限公司 2022-10-04 CN claimed
CN-111303762-B Gold-imitating ceramic film coating applied to ceramic and preparation method 佛山市明朝科技开发有限公司 2021-10-22 CN claimed
US-20210170356-A1 FUNCTIONALIZED SURFACES AND PREPARATION THEREOF Twist Bioscience Corporation 2021-06-10 US claimed
US-10987648-B2 Functionalized surfaces and preparation thereof Twist Bioscience Corporation (US) 2021-04-27 US claimed
US-20200299322-A1 METHODS AND DEVICES FOR DE NOVO OLIGONUCLEIC ACID ASSEMBLY Twist Bioscience Corporation 2020-09-24 US claimed
CN-110669431-B High-adhesion acid-and-alkali-resistant ceramic film coating and preparation method thereof 佛山市明朝科技开发有限公司 2020-07-28 CN claimed
CN-111303762-A Gold-imitating ceramic film coating applied to ceramic and preparation method 佛山市明朝科技开发有限公司 2020-06-19 CN claimed
EP-3384077-A1 FUNCTIONALIZED SURFACES AND PREPARATION THEREOF Twist Bioscience Corporation (US) 2018-10-10 EP claimed
CN-108603307-A Functionalized surfaces and preparation thereof 特韦斯特生物科学公司 2018-09-28 CN claimed
US-20180126355-A1 FUNCTIONALIZED SURFACES AND PREPARATION THEREOF Twist Bioscience Corporation 2018-05-10 US claimed
US-20180104664-A1 TEXTURED SURFACES FOR POLYNUCLEOTIDE SYNTHESIS Twist Bioscience Corporation 2018-04-19 US claimed
WO-2018026920-A1 TEXTURED SURFACES FOR POLYNUCLEOTIDE SYNTHESIS Twist Bioscience Corporation (US) 2018-02-08 WO claimed
WO-2017095958-A1 FUNCTIONALIZED SURFACES AND PREPARATION THEREOF Twist Bioscience Corporation (US) 2017-06-08 WO claimed
WO-2016126882-A1 METHODS AND DEVICES FOR DE NOVO OLIGONUCLEIC ACID ASSEMBLY Twist Bioscience Corporation (US) 2016-08-11 WO claimed
US-20160229884-A1 METHODS AND DEVICES FOR DE NOVO OLIGONUCLEIC ACID ASSEMBLY Twist Bioscience Corporation 2016-08-11 US claimed
US-20090283671-A1 Multi-channel electrospray emitter QUEEN'S UNIVERSITY AT KINGSTON (CA) 2009-11-19 US claimed
WO-2009114951-A1 MULTI-CHANNEL ELECTROSPRAY EMITTER QUEEN'S UNIVERSITY AT KINGSTON (CA) 2009-09-24 WO claimed