Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662644 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL15796294 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL10833640 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL17966562 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL9438692 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL4358183 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL812441 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL7649056 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL303415 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL132944 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100150809-A1 | ENHANCEMENTS FOR A CHLOROSILANE REDISTRIBUTION REACTOR | DYNAMIC ENGINEERING INC. | 2010-06-17 | — | — | US | claimed |
| US-20160347777-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2016-12-01 | — | — | US | disclosed |
| CN-202430015-U | Disproportionation reactor and device containing reactor for transforming SiH2Cl2 to SiHCl3 | WP ENERGY EQUIPMENT & TECHNOLOGY CO LTD | 2012-09-12 | — | — | CN | disclosed |
| US-20100150809-A1 | ENHANCEMENTS FOR A CHLOROSILANE REDISTRIBUTION REACTOR | DYNAMIC ENGINEERING INC. | 2010-06-17 | — | — | US | disclosed |
| US-20050079337-A1 | Porous body and method of making the porous body | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2005-04-14 | — | — | US | disclosed |
| CN-1108525-C | Alkyl ether type high performance liquid chromatography reversed phase filler and preparation method thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2003-05-14 | — | — | CN | disclosed |
| CN-1283792-A | Alkyl ether type high performance liquid chromatography reversed phase filler and preparation method thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2001-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347777-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | OR51E2, RIF1, SRMS | TSHR 3595/4885THRB 3098/4885ALDH1A1 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.