Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | MIF | P14174 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543288 | 1.00 | TAAR1 (0.62) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL16298283 | 0.93 | TAAR1 (0.59) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL7384474 | 0.93 | TAAR1 (0.59) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL177514 | 0.89 | TAAR1 (0.67) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL30186510 | 0.89 | TAAR1 (0.67) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL11383498 | 0.83 | TAAR1 (0.65) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL4664652 | 0.81 | TAAR1 (0.62) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL1723183 | 0.81 | TAAR1 (0.62) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL1046263 | 0.81 | TAAR1 (0.62) | TAAR1MIFHDAC1HDAC8IDO1 | |
| SCHEMBL21913967 | 0.81 | TAAR1 (0.62) | TAAR1MIFHDAC1HDAC8IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104774134-A | Synthetic method of cinacalcet hydrochloride and intermediate compound of cinacalcet hydrochloride | Chengdu zihao pharmaceutical co ltd | 2015-07-15 | — | — | CN | claimed |
| US-8969623-B2 | Method for the preparation of cinacalcet and intermediates and impurities thereof | Amneal Pharmaceuticals, LLC (US) | 2015-03-03 | — | — | US | claimed |
| CN-103044267-A | Preparation method of high-purity cinacalcet hydrochloride | CHINA RESOURCES SAIKE PHARMACEUTICAL CO LTD | 2013-04-17 | — | — | CN | claimed |
| EP-2406211-A2 | A NEW METHOD FOR THE PREPARATION OF CINACALCET AND NEW INTERMEDIATES THEREOF | Megafine Pharma (P) Ltd. (IN) | 2012-01-18 | — | — | EP | claimed |
| WO-2010103531-A2 | A NEW METHOD FOR THE PREPARATION OF CINACALCET AND NEW INTERMEDIATES THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2010-09-16 | — | — | WO | claimed |
| CN-120365778-A | High-weather-resistance photovoltaic panel coating material and preparation method thereof | 斯科瑞新材料科技(山东)股份有限公司 | 2025-07-25 | — | — | CN | disclosed |
| WO-2024145659-A1 | HETEROCYCLE FUSED GAMMA-CARBOLINES ACTING ON THE SEROTONINE 5-HT2A RECEPTOR | INTRA-CELLULAR THERAPIES, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| US-11535647-B2 | Peptide purification method using sulfonate compound | NAGASE & CO., LTD. (JP) | 2022-12-27 | — | — | US | disclosed |
| CN-112321451-B | Method for preparing cinacalcet hydrochloride drug intermediate | 福建海西新药创制有限公司 | 2022-08-23 | — | — | CN | disclosed |
| US-20220144888-A1 | PEPTIDE PURIFICATION METHOD USING SULFONATE COMPOUND | NAGASE & CO., LTD. (JP) | 2022-05-12 | — | — | US | disclosed |
| CN-112321451-A | Method for preparing cinacalcet hydrochloride drug intermediate | 福建海西新药创制有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-111018734-B | Synthesis method of cinacalcet hydrochloride intermediate | 福建海西新药创制有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-101730677-A | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-06-09 | — | — | CN | disclosed |
| EP-2168944-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |
| WO-2010010359-A2 | A PROCESS FOR THE PREPARATION OF CINACALCET AND ITS SALTS | CILPA LIMITED (IN) | 2010-01-28 | — | — | WO | disclosed |
| WO-2008058235-A2 | PROCESSES FOR THE PREPARATION OF CINACALCET | DR. REDDY'S LABORATORIES, LTD. (IN) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008058236-A2 | METHODS FOR PREPARING CINACALCET HYDROCHLORIDE | DR. REDDY'S LABORTORIES, LTD. (IN) | 2008-05-15 | — | — | WO | disclosed |
| WO-2006082412-A2 | MULTIMERS OF PYRIMIDINONE DERIVATIVES AND THEIR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | ARGENTA DISCOVERY LIMITED (GB) | 2006-08-10 | — | — | WO | disclosed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144888-A1 | PEPTIDE PURIFICATION METHOD USING SULFONATE COMPOUND | VIP, IAPP, RPS27A | TAAR1 4329/4885MIF 2589/4885HDAC1 3514/4885 |
| US-11535647-B2 | Peptide purification method using sulfonate compound | VIP, IAPP, RPS27A | TAAR1 4329/4885MIF 2589/4885HDAC1 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.