Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.37 |
| ▸ | PGK2 | P07205 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 7/20 | 0.33 |
| ▸ | RAB9A | P51151 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107675 | 0.78 | NOTUM (0.41) | DAOMRGPRX4NPC1RAB9A | |
| SCHEMBL14069079 | 0.75 | RAB9A (0.40) | DAONPC1RAB9A | |
| SCHEMBL11394538 | 0.75 | EPHX2 (0.42) | PGK1PGK2NPC1RAB9A | |
| SCHEMBL8123885 | 0.74 | MEN1 (0.35) | DAOMRGPRX4NPC1RAB9A | |
| SCHEMBL12489570 | 0.73 | DAO (0.33) | DAOMRGPRX4NPC1RAB9A | |
| SCHEMBL8123162 | 0.73 | DAO (0.34) | DAOMRGPRX4NPC1RAB9A | |
| SCHEMBL8123160 | 0.72 | DAO (0.33) | DAONPC1RAB9A | |
| SCHEMBL23124029 | 0.71 | DAO (0.32) | DAOMRGPRX4NPC1RAB9A | |
| SCHEMBL11387029 | 0.71 | MAPT (0.42) | — | |
| SCHEMBL6608431 | 0.70 | CHRM1 (0.36) | PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691962-B1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| EP-0691962-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022842-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |