Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26597106 | 0.88 | POLB (0.52) | CCR2POLBMAPTATMCYP19A1 | |
| SCHEMBL6018883 | 0.88 | CCR2 (0.61) | CCR2POLBMAPTCYP19A1KMT2A | |
| SCHEMBL1415761 | 0.85 | CCR2 (0.63) | CCR2MAPTCYP19A1KMT2ACYP1A2 | |
| SCHEMBL15712743 | 0.82 | CCR2 (0.77) | CCR2 | |
| SCHEMBL15712653 | 0.82 | CCR2 (0.60) | CCR2POLBMAPTCYP19A1KMT2A | |
| SCHEMBL8131716 | 0.81 | MAPT (0.50) | CCR2POLBMAPTATMCYP19A1 | |
| SCHEMBL3052651 | 0.80 | CYP19A1 (0.59) | CCR2MAPTCYP19A1KMT2AALDH1A1 | |
| SCHEMBL6301018 | 0.80 | CCR2 (0.85) | CCR2 | |
| SCHEMBL2122743 | 0.79 | CYP19A1 (0.66) | CCR2POLBMAPTATMCYP19A1 | |
| SCHEMBL8124443 | 0.79 | CCR2 (0.56) | CCR2CYP19A1ALDH1A1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049701-A1 | TRICYCLIC INDOLENE SUBSTITUTED OXAZOLIDINONES | BAYER AG (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037652-A1 | TRICYCLIC INDOLENE SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |