Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.80 |
| ▸ | DRD2 | P14416 | 2/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125940 | 0.96 | SIGMAR1 (0.74) | SIGMAR1DRD2DRD3 | |
| SCHEMBL11890531 | 0.96 | SIGMAR1 (0.74) | SIGMAR1DRD2DRD3 | |
| SCHEMBL8124961 | 0.96 | SIGMAR1 (0.74) | SIGMAR1DRD2DRD3 | |
| SCHEMBL8118341 | 0.90 | SIGMAR1 (0.65) | SIGMAR1DRD2DRD3CXCR6 | |
| SCHEMBL8119845 | 0.89 | SIGMAR1 (0.64) | SIGMAR1DRD2DRD3 | |
| SCHEMBL8117971 | 0.89 | SIGMAR1 (1.00) | SIGMAR1DRD2DRD3 | |
| SCHEMBL8126235 | 0.86 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD3CXCR6 | |
| SCHEMBL8127075 | 0.86 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD3CXCR6 | |
| SCHEMBL8120009 | 0.86 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD3 | |
| SCHEMBL8118831 | 0.86 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD3HTR3AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861252-B1 | NAPHTHAMIDE DERIVATIVES OF 3 BETA-AMINO AZABICYCLO OCTANE OR NONANE AS NEUROLEPTIC AGENTS | PF MEDICAMENT (FR) | 2000-02-23 | — | — | EP | claimed |