SCHEMBL812652

SCHEMBL812652

COCC(COC)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
NPSR1 Q6W5P4 3/20 0.37
CYP19A1 P11511 3/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
LMNA P02545 3/20 0.36
CYP2A6 P11509 1/20 0.36
MIF P14174 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7068616 0.80 MEN1 (0.41) MEN1KMT2AGRIN2DGRIN3BGRIN1
SCHEMBL5230026 0.79 CYP19A1 (0.39) MEN1KMT2AGRIN2DGRIN3BGRIN1
SCHEMBL813010 0.79 TSHR (0.44) TSHRCYP19A1ESR1ESR2ALDH1A1
SCHEMBL29174538 0.77 MEN1 (0.43) MEN1KMT2AGRIN2DGRIN3BGRIN1
SCHEMBL235054 0.76 MAPK1 (0.42) TSHRMAPK1ALDH1A1
SCHEMBL7067388 0.74 NR1H2 (0.44) ESR1ESR2
SCHEMBL28931715 0.74 GRIN2D (0.37) MEN1KMT2AGRIN2DGRIN3BGRIN1
SCHEMBL29106876 0.71 CYP19A1 (0.37) MEN1KMT2AGRIN2DGRIN3BGRIN1
SCHEMBL11218539 0.70 GRIN2D (0.56) MEN1KMT2AGRIN2DGRIN3BGRIN1
SCHEMBL7064011 0.70 CYP3A4 (0.44) ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024008770-A1 CATALYST SYSTEM FOR POLYMERIZATION OF AN OLEFIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-11 WO claimed
WO-2023104940-A1 CATALYST SYSTEM FOR POLYMERIZATION OF AN OLEFIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-06-15 WO claimed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
CN-113754802-B Catalyst system for olefin polymerization reaction and prepolymerization catalyst composition 中国石油化工股份有限公司 2023-03-31 CN claimed
CN-113754801-B Solid catalyst for preparing olefin polymer and solid catalyst system 中国石油化工股份有限公司 2023-02-28 CN claimed
CN-113754803-B Catalyst system and application thereof as catalyst for olefin polymerization 中国石油化工股份有限公司 2023-02-24 CN claimed
US-11434315-B2 Propylene polymerizing solid catalyst for reducing VOC and method of producing polypropylene using same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2022-09-06 US claimed
EP-3083719-B1 CATALYST SYSTEM FOR POLYMERIZATION OF AN OLEFIN SAUDI BASIC IND CORP (SA) 2018-12-19 EP claimed
US-9944731-B2 Catalyst system for polymerization of an olefin SAUDI BASIC INDUSTRIES CORPORATION (SA) 2018-04-17 US claimed
US-20160311947-A1 CATALYST SYSTEM FOR POLYMERIZATION OF AN OLEFIN SAUDI BASIC INDUSTRIES CORPORATION (SA) 2016-10-27 US claimed
EP-1260523-B1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORP (CN) 2013-01-23 EP claimed
US-6683017-B2 SOLID CATALYST COMPONENT COMPRISING TITANIUM, MAGNESIUM, HALOGEN AND A 1,3-DIETHER, ORGANIC ALUMINUM COMPOUND, ORGANIC SILICON COMPOUND CHINA PETRO - CHEMICAL CORPORATION (CN) 2004-01-27 US claimed
EP-0891988-B1 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE SPA (IT) 2003-06-04 EP claimed
EP-1260523-A1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORPORATION (CN) 2002-11-27 EP claimed
US-20010025006-A1 Catalyst system for the (co) polymerization of olefins BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, SINOPEC (CN) 2001-09-27 US claimed
US-20260092131-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2026-04-02 US disclosed
EP-4594371-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2025-08-06 EP disclosed
EP-0362705-A2 Catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-11 EP disclosed
EP-0361494-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092131-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS ZDHHC7, DNER, MDM4 MEN1 4514/4885KMT2A 2996/4885GRIN2D 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.