Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813010 | 0.76 | TSHR (0.44) | ESR1ESR2 | |
| SCHEMBL812652 | 0.74 | MEN1 (0.43) | ESR1ESR2 | |
| SCHEMBL235054 | 0.73 | MAPK1 (0.42) | — | |
| SCHEMBL13955525 | 0.69 | NR1H2 (0.56) | NR1H2NR1H3 | |
| SCHEMBL586534 | 0.68 | NR1H2 (0.50) | NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL12688243 | 0.67 | NR1H2 (0.54) | NR1H2NR1H3 | |
| SCHEMBL12773794 | 0.67 | NR1H2 (0.60) | NR1H2NR1H3 | |
| SCHEMBL7064011 | 0.67 | CYP3A4 (0.44) | ESR1ESR2 | |
| SCHEMBL15899297 | 0.66 | NR1H2 (0.52) | NR1H2NR1H3 | |
| SCHEMBL13141791 | 0.65 | NR1H2 (0.47) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |