SCHEMBL812698

SCHEMBL812698

O=S(=O)(NC1CCCCC1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.78
KDM4E B2RXH2 2/20 0.78
RECQL P46063 1/20 0.78
ALDH1A1 P00352 9/20 0.69
TSHR P16473 2/20 0.69
MAPK1 P28482 2/20 0.69
HTT P42858 2/20 0.69
CYP3A4 P08684 1/20 0.69
LMNA P02545 6/20 0.63
HPGD P15428 2/20 0.63
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
NPSR1 Q6W5P4 1/20 0.59
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8396710 1.00 SMN1; SMN2 (0.78) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
SCHEMBL11707518 1.00 SMN1; SMN2 (0.78) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
SCHEMBL7648169 0.98 KDM4E (0.81) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
Hydrochloric Acid SCHEMBL7254237 0.96 KDM4E (0.78) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
Bicarbonate SCHEMBL15225914 0.95 SMN1; SMN2 (0.70) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
SCHEMBL4041413 0.94 KDM4E (0.74) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
SCHEMBL8355420 0.90 KDM4E (0.67) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
SCHEMBL2225334 0.90 KDM4E (0.67) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
SCHEMBL12418061 0.90 KDM4E (0.73) SMN1; SMN2KDM4ERECQLALDH1A1TSHR
SCHEMBL12418055 0.90 KDM4E (0.73) SMN1; SMN2KDM4ERECQLALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3127937-B1 FLAME RESISTANT POLYAMIDE 12 SUBSTANCES FOR RAIL APPLICATIONS EMS PATENT AG (CH) 2018-03-07 EP claimed
CN-107001283-A Flt3 receptor antagonists 国家健康与医学研究院 2017-08-01 CN claimed
CN-106433106-A Flame-retardant polyamide 12 moulding composition for railway applications EMS 专利股份公司 2017-02-22 CN claimed
US-20170037198-A1 FLAME-RETARDANT POLYAMIDE 12 MOULDING COMPOSITION FOR RAILWAY APPLICATIONS EMS-PATENT AG (CH) 2017-02-09 US claimed
EP-3127937-A1 FLAME RESISTANT POLYAMIDE 12 SUBSTANCES FOR RAIL APPLICATIONS EMS-PATENT AG (CH) 2017-02-08 EP claimed
EP-2325260-B1 Semi-aromatic moulding masses and their applications EMS PATENT AG (CH) 2016-04-27 EP claimed
CN-102070902-B Semi-aromatic moulding masses and uses thereof EMS PATENT AG (CH) 2015-11-25 CN claimed
EP-1616859-B1 Substituted cyclohexyl carboxylic acid compounds SEIKAGAKU KOGYO CO LTD (JP) 2013-09-04 EP claimed
CN-103254190-A Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors INCYTE CORP 2013-08-21 CN claimed
CN-103214484-A Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors INCYTE CORP A DELAWARE CORP 2013-07-24 CN claimed
CN-103012154-A Method for preparing organic amine through benzsulfamide derivative ammonolysis UNIV ZHEJIANG 2013-04-03 CN claimed
CN-103012221-A Preparation method of benzene sulfonic amide derivatives UNIV ZHEJIANG 2013-04-03 CN claimed
US-20110123749-A1 SEMIAROMATIC MOULDING COMPOSITIONS AND USES OF THESE EMS-PATENT AG (CH) 2011-05-26 US claimed
EP-2325260-A1 Semi-aromatic moulding masses and their applications EMS-PATENT AG (CH) 2011-05-25 EP claimed
CN-102070902-A Semi-aromatic moulding masses and their applications EMS PATENT AG 2011-05-25 CN claimed
CN-101448826-A Heteroaryl substituted pyrrolo [2 ] as janus kinase inhibitors INCYTE CORP (US) 2009-06-03 CN claimed
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 EP claimed
US-4339372-A Process of preparing stabilized polychloroprene latex DISTUGIL (FR) 1982-07-13 US claimed